New Tools to Study Contact Activation

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New Tools to Study Contact Activation

The recent availability of a sensitive chromogenic method approach for determination of FXIa activity has been explored for designing sensitive methods for FXIIa and kallikrein, both using FXa formation as the read-out. For both enzymes the assay range 1-10 nmol/L provides a resolution of about 0.8 absorbance units with a total assay time of about 20 min. For studies on activation kinetics, sub...

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ژورنال

عنوان ژورنال: Frontiers in Medicine

سال: 2016

ISSN: 2296-858X

DOI: 10.3389/fmed.2016.00058